A new restaurant hopes to “Harvest” a crop of culinary enthusiasts as loyal as those who made the Saugatuck site’s previous dining landmark a local favorite for nearly half a century.

After seven months renovating the Railroad Place property where Mario’s closed after 48 years last spring, Harvest wine bar and restaurant has arrived at the track-side venue. It is the third Harvest to be opened by the Siguenza family, who operate two others in Greenwich and New Haven, as well as three other restaurants in Fairfield County.

Harvest — promoting “custom cuisine from farm to fork” — is part of “a family business,” said Vicente Siguenza. “I think we always wanted to do something in Westport, it just never came about.”

Until now.

Harvest, which opened last week, will feature what Siguenza calls new American fare, with offerings that range from steamed mussels, homemade meatballs and white cheddar shrimp and grits, to shaved Brussels sprouts salad and steak tartare, to lamb papardelle, homemade pastas, roasted half-chicken scarpariello, seafood pan roast and wood-fire Harvest burger.

The food can be accompanied by an extensive selection wine and cocktails.

“Westport is a big foodie town,” Siguenza said. “People know good food in Westport.”

“Our goal is to do seven lunches and seven dinners a week, with brunch on Saturdays and Sundays,” he said, although for at least the next month Harvest will serve only dinner, seven days a week.

“My goal is really to fit old Mario’s customers in,” he said. “Hopefully we do it to their standards, and hopefully new customers come, too.”

Harvest wine bar and restaurant, 36 Railroad Place, is open seven days a week for dinner, from 5 to 11 p.m. For more information, call 203-221-0810 or visit www.harvestwinebar.com .